one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity connected to bortezomib, a proteasome inhibitor Utilized in the treatment method of various myeloma. Its synthesis or review is important for making certain the purity and safety with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-one): A vital compound while in the synthesis of imatinib, a drug that targets specific different types of cancer, which include Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers for instance breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their research is crucial for optimizing the production method and making certain higher purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is used to deal with breast cancer, and these intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Employed in the cure of breast most cancers. Many intermediates assist CAS NO. 155405-80-4 in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug effective in treating cancers which include ovarian, breast, and lung cancer.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the procedure of colorectal most cancers and tiny mobile lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-eighty two-9): This compound is linked to the synthesis of adamantane derivatives, which have several applications, including antiviral CAS NO. 314771-76-1 Qualities.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for kind 2 diabetic issues that inhibits the enzyme DPP-four to regulate blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked to the synthesis of various gluconic acid derivatives, which are Utilized in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate two: A precursor inside the synthesis of canagliflozin, a medication made use of to manage type 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).